|Storage||Cool & Dry Place|
|Dosage||As per doctor’s prescription|
|Pack Size||5×2 ml|
What is a Methylcobalamin Injection?
Methylcobalamin is a water-soluble organometallic compound with a trivalent cobalt ion bound inside a corrin ring. Even though it is similar to the porphyrin ring found in chlorophyll, heme and cytochrome, Methylcobalamin has its two pyrrole rings directly bound to each other making Cobalt (Co) the central metal ion. Plants and animals can not manufacture methylcobalamin. Only two organisms have the enzymes that are required for these processes, i.e. archaea and bacteria.
Mechanisms & Mode of Action of the Methylcobalamin Injection
Vitamin B12 in is assimilated in the body in two forms. These include; Methylcobalamin and 5-deoxyadenosyl cobalamin. Methylcobalamin acts as a cofactor of enzyme methionine synthase which is involved in the conversion of amino acid homocysteine into active methionine which is important for DNA methylation. The other form of Vitamin B12, 5-deoxyadenosyl cobalamin is also a co-factor which is essential to the enzyme that converts L-methylmalonyl-CoA into Succinyl-CoA. This conversion is very important since it facilitates the various processes which take part in the extraction of energy from fats and proteins in the body. Additionally, Succinyl-CoA is required in the production of haemoglobin, a substance found in the red blood cells that help it to carry and transport oxygen.
The possible side effects of Methylcobalamin B12 Injections
In many cases, methylcobalamin is not toxic even in large doses. The adverse side effects that have been reported from the administration of this medication include; headaches, paresthesias, nausea or vomiting, and rhinitis. Some reactions due to an intramuscular injection can include; mild diarrhoea, nervousness, anxiety, ataxia, pruritus and swelling of some parts or your whole body.